Treating skin or nail infections caused by fungi, including yeasts and some bacteria. Infection may appear on: the trunk. hands or feet. scalp or outer ear. Miconase works to eliminate fungi and accompanying bacteria that may be present. Infections of the vagina and the skin around the vagina (signs of this infection include itching, redness, and white discharge). Miconase works by killing the fungus causing the infection and some bacteria that may also be present.